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    ESR1 estrogen receptor 1 [ Equus asinus (ass) ]

    Gene ID: 106822682, updated on 19-Jun-2024

    Summary

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    Gene symbol
    ESR1
    Gene description
    estrogen receptor 1
    See related
    Ensembl:ENSEASG00005018755
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus asinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See ESR1 in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    101 current ASM1607732v2 (GCF_016077325.2) 28 NC_052204.1 (11365658..11618223)
    100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014638467.1 (268880..521723, complement)

    Chromosome 28 - NC_052204.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 170 Neighboring gene uncharacterized LOC123281782 Neighboring gene uncharacterized LOC123281653 Neighboring gene uncharacterized LOC106822684 Neighboring gene uncharacterized LOC123281725 Neighboring gene spectrin repeat containing nuclear envelope protein 1 Neighboring gene uncharacterized LOC123281726

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear estrogen receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in steroid hormone receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    estrogen receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1607732v2

    Genomic

    1. NC_052204.1 Reference ASM1607732v2

      Range
      11365658..11618223
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014827964.2 → XP_014683450.1  estrogen receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C4MJM9
      Conserved Domains (4) summary
      cd06949
      Location:310 → 569
      NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
      cd07171
      Location:180 → 261
      NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
      pfam02159
      Location:42 → 181
      Oest_recep; Oestrogen receptor
      pfam12743
      Location:578 → 617
      ESR1_C; Oestrogen-type nuclear receptor final C-terminal

    2. XM_044761322.1 → XP_044617257.1  estrogen receptor isoform X4

      Conserved Domains (2) summary
      cd07171
      Location:180 → 261
      NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
      cl11397
      Location:310 → 457
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    3. XM_044761321.1 → XP_044617256.1  estrogen receptor isoform X3

      Conserved Domains (2) summary
      cd07171
      Location:180 → 261
      NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
      cl11397
      Location:310 → 456
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    4. XM_014827966.2 → XP_014683452.1  estrogen receptor isoform X2

      UniProtKB/TrEMBL
      A0A8C4MI61, A0A8C4MJM9
      Related
      ENSEASP00005027600.1, ENSEAST00005029976.2
      Conserved Domains (4) summary
      cd06949
      Location:310 → 547
      NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
      cd07171
      Location:180 → 261
      NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
      pfam02159
      Location:42 → 181
      Oest_recep; Oestrogen receptor
      pfam12743
      Location:556 → 595
      ESR1_C; Oestrogen-type nuclear receptor final C-terminal
    Nucleotide Protein
    Heading Accession and Version

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