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    GCAWKR gastric cancer associated WDR5 and KAT2A binding lncRNA [ Homo sapiens (human) ]

    Gene ID: 105369201, updated on 10-Dec-2024

    Summary

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    Official Symbol
    GCAWKRprovided by HGNC
    Official Full Name
    gastric cancer associated WDR5 and KAT2A binding lncRNAprovided by HGNC
    Primary source
    HGNC:HGNC:53740
    See related
    Ensembl:ENSG00000272808 AllianceGenome:HGNC:53740
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    all
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    Genomic context

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    See GCAWKR in Genome Data Viewer
    Location:
    15q26.3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (100849752..100876878)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (98604807..98631936)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (101389957..101417083)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371024 Neighboring gene MPRA-validated peak2455 silencer Neighboring gene protein enabled homolog Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr15:101342428-101343627 Neighboring gene Sharpr-MPRA regulatory region 9420 Neighboring gene PHF5A pseudogene 6 Neighboring gene collagen alpha-1(I) chain-like Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6879 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:101420568-101421082 Neighboring gene aldehyde dehydrogenase 1 family member A3 Neighboring gene ALDH1A3 antisense RNA 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. lncRNA GCAWKR Promotes Gastric Cancer Development by Scaffolding the Chromatin Modification Factors WDR5 and KAT2A. Ma M, et al. Mol Ther, 2018 Nov 7. PMID 30274785, Free PMC Article
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    General gene information

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    Homology

    Clone Names

    • FLJ31972, MGC126654, MGC150974

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_160702.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC015712

    2. NR_160703.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC015712
      Related
      ENST00000647806.1

    3. NR_160704.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC015712

    4. NR_160705.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC015712

    5. NR_160706.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC015712

    6. NR_160707.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC015712

    7. NR_160708.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC015712

    8. NR_160709.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC015712

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      100849752..100876878
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      98604807..98631936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials