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    adap2 ArfGAP with dual PH domains 2 [ Callorhinchus milii (elephant shark) ]

    Gene ID: 103175407, updated on 11-Mar-2024

    Summary

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    Gene symbol
    adap2
    Gene description
    ArfGAP with dual PH domains 2
    See related
    Ensembl:ENSCMIG00000016900
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Callorhinchus milii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    zebrafish all
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    Genomic context

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    See adap2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    101 current IMCB_Cmil_1.0 (GCF_018977255.1) Unplaced Scaffold NW_024704761.1 (11589010..11606322, complement)
    100 previous assembly Callorhinchus_milii-6.1.3 (GCF_000165045.1) Unplaced Scaffold NW_006890063.1 (191452..211529)

    NW_024704761.1Genomic Context describing neighboring genes Neighboring gene chromosome unknown C17orf75 homolog Neighboring gene BUB3-interacting and GLEBS motif-containing protein ZNF207 Neighboring gene transcription elongation factor, mitochondrial Neighboring gene ATPase family AAA domain containing 5a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequencing and analysis of full-length cDNAs, 5'-ESTs and 3'-ESTs from a cartilaginous fish, the elephant shark (Callorhinchus milii). Tan YY, et al. PLoS One, 2012. PMID 23056606, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with dual PH domain-containing protein 2
    Names
    arf-GAP with dual PH domain-containing protein 1
    arf-GAP with dual PH domain-containing protein 1-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001292992.1 → NP_001279921.1  arf-GAP with dual PH domain-containing protein 2

      See identical proteins and their annotated locations for NP_001279921.1

      Status: PROVISIONAL

      Source sequence(s)
      JX052493
      UniProtKB/TrEMBL
      A0A4W3JR12, K4G064
      Conserved Domains (4) summary
      cd01251
      Location:256 → 361
      PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
      cd13252
      Location:135 → 242
      PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
      pfam00169
      Location:259 → 361
      PH; PH domain
      pfam01412
      Location:9 → 125
      ArfGap; Putative GTPase activating protein for Arf

    RefSeqs of Annotated Genomes: Callorhinchus milii Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference IMCB_Cmil_1.0 Primary Assembly

    Genomic

    1. NW_024704761.1 Reference IMCB_Cmil_1.0 Primary Assembly

      Range
      11589010..11606322 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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