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    LOC102693295 pro-neuregulin-2, membrane-bound isoform [ Lepisosteus oculatus (spotted gar) ]

    Gene ID: 102693295, updated on 21-Oct-2024

    Summary

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    Gene symbol
    LOC102693295
    Gene description
    pro-neuregulin-2, membrane-bound isoform
    See related
    Ensembl:ENSLOCG00000012632
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Lepisosteus oculatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae; Lepisosteus
    Also known as
    nrg2
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    Genomic context

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    See LOC102693295 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_09 current fLepOcu1.hap2 (GCF_040954835.1) 11 NC_090706.1 (41764716..42067431, complement)
    101 previous assembly LepOcu1 (GCF_000242695.1) Linkage Group LG6 NC_023184.1 (40406347..40709154, complement)

    Chromosome 11 - NC_090706.1Genomic Context describing neighboring genes Neighboring gene SH2 domain-containing protein 4A-like Neighboring gene pleckstrin and Sec7 domain containing 2 Neighboring gene purine-rich element binding protein Aa Neighboring gene uncharacterized LOC138241830

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pro-neuregulin-2, membrane-bound isoform
    Names
    neuregulin 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_040954835.1-RS_2024_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fLepOcu1.hap2

    Genomic

    1. NC_090706.1 Reference fLepOcu1.hap2

      Range
      41764716..42067431 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015349952.2 → XP_015205438.1  pro-neuregulin-2, membrane-bound isoform isoform X3

      Conserved Domains (4) summary
      PHA03099
      Location:243 → 331
      PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
      pfam07679
      Location:142 → 228
      I-set; Immunoglobulin I-set domain
      pfam02158
      Location:292 → 693
      Neuregulin; Neuregulin family
      cl11960
      Location:156 → 226
      Ig; Immunoglobulin domain

    2. XM_006631957.3 → XP_006632020.1  pro-neuregulin-2, membrane-bound isoform isoform X1

      Conserved Domains (4) summary
      cd00054
      Location:253 → 282
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07679
      Location:142 → 228
      I-set; Immunoglobulin I-set domain
      pfam02158
      Location:300 → 701
      Neuregulin; Neuregulin family
      cl11960
      Location:156 → 226
      Ig; Immunoglobulin domain

    3. XM_015349951.2 → XP_015205437.1  pro-neuregulin-2, membrane-bound isoform isoform X2

      Conserved Domains (4) summary
      cd00054
      Location:253 → 281
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07679
      Location:142 → 228
      I-set; Immunoglobulin I-set domain
      pfam02158
      Location:298 → 699
      Neuregulin; Neuregulin family
      cl11960
      Location:156 → 226
      Ig; Immunoglobulin domain

    4. XM_015349953.2 → XP_015205439.1  pro-neuregulin-2, membrane-bound isoform isoform X4

      UniProtKB/TrEMBL
      W5N4J3
      Related
      ENSLOCP00000015552.1
      Conserved Domains (4) summary
      cd00054
      Location:142 → 170
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07679
      Location:31 → 117
      I-set; Immunoglobulin I-set domain
      pfam02158
      Location:195 → 596
      Neuregulin; Neuregulin family
      cl11960
      Location:45 → 115
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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