U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    IBTK inhibitor of Bruton tyrosine kinase [ Pelodiscus sinensis (Chinese soft-shelled turtle) ]

    Gene ID: 102450312, updated on 10-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    IBTK
    Gene description
    inhibitor of Bruton tyrosine kinase
    See related
    Ensembl:ENSPSIG00000007073
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pelodiscus sinensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia; Trionychidae; Pelodiscus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See IBTK in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    102 current PelSin_1.0 (GCF_000230535.1) Unplaced Scaffold NW_005853167.1 (847054..969561, complement)

    NW_005853167.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112544621 Neighboring gene uncharacterized LOC112544620 Neighboring gene uncharacterized LOC112544624 Neighboring gene trophoblast glycoprotein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_005853167 Unplaced Scaffold Reference PelSin_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine kinase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    inhibitor of Bruton tyrosine kinase

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Pelodiscus sinensis Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference PelSin_1.0 Primary Assembly

    Genomic

    1. NW_005853167.1 Reference PelSin_1.0 Primary Assembly

      Range
      847054..969561 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006115893.3 → XP_006115955.1  inhibitor of Bruton tyrosine kinase isoform X1

      UniProtKB/TrEMBL
      K7FI34
      Related
      ENSPSIP00000007694.1, ENSPSIT00000007735.1
      Conserved Domains (7) summary
      smart00225
      Location:771 → 866
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cd00204
      Location:47 → 129
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd14821
      Location:873 → 926
      SPOP_C_like; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins
      pfam00415
      Location:248 → 300
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00651
      Location:762 → 869
      BTB; BTB/POZ domain
      pfam12796
      Location:25 → 117
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:51 → 83
      ANK; ANK repeat [structural motif]

    2. XM_006115894.3 → XP_006115956.1  inhibitor of Bruton tyrosine kinase isoform X2

      Conserved Domains (7) summary
      smart00225
      Location:771 → 866
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cd00204
      Location:47 → 129
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd14821
      Location:873 → 926
      SPOP_C_like; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins
      pfam00415
      Location:248 → 300
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00651
      Location:762 → 869
      BTB; BTB/POZ domain
      pfam12796
      Location:25 → 117
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:51 → 83
      ANK; ANK repeat [structural motif]

    3. XM_006115895.3 → XP_006115957.1  inhibitor of Bruton tyrosine kinase isoform X3

      Conserved Domains (7) summary
      smart00225
      Location:771 → 866
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cd00204
      Location:47 → 129
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd14821
      Location:873 → 926
      SPOP_C_like; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins
      pfam00415
      Location:248 → 300
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00651
      Location:762 → 869
      BTB; BTB/POZ domain
      pfam12796
      Location:25 → 117
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:51 → 83
      ANK; ANK repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.