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    CNOT6 CCR4-NOT transcription complex subunit 6 [ Macaca fascicularis (crab-eating macaque) ]

    Gene ID: 102121928, updated on 1-Aug-2024

    Summary

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    Gene symbol
    CNOT6
    Gene description
    CCR4-NOT transcription complex subunit 6
    See related
    Ensembl:ENSMFAG00000030867
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca fascicularis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CNOT6 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 6 NC_088380.1 (187402233..187488272)
    102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 6 NC_052260.1 (175576780..175662789)

    Chromosome 6 - NC_088380.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC135971532 Neighboring gene U6 spliceosomal RNA Neighboring gene nascent polypeptide-associated complex subunit alpha, muscle-specific form-like Neighboring gene secretoglobin family 3A member 1 Neighboring gene fms related receptor tyrosine kinase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables poly(A)-specific ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA poly(A) tail shortening IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CCR4-NOT complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CCR4-NOT transcription complex subunit 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MFA8v1.0

    Genomic

    1. NC_088380.1 Reference T2T-MFA8v1.0

      Range
      187402233..187488272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_045394669.2 → XP_045250604.1  CCR4-NOT transcription complex subunit 6 isoform X1

      UniProtKB/TrEMBL
      A0A2K5US79, A0A8J8XS73, G7P737
      Conserved Domains (3) summary
      cd10313
      Location:191 → 540
      Deadenylase_CCR4a; C-terminal deadenylase domain of CCR4a, also known as CCR4-NOT transcription complex subunit 6
      COG4886
      Location:52 → 159
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:33 → 52
      LRR_1; leucine-rich repeat [structural motif]

    2. XM_005558808.4 → XP_005558865.1  CCR4-NOT transcription complex subunit 6 isoform X1

      See identical proteins and their annotated locations for XP_005558865.1

      UniProtKB/TrEMBL
      A0A2K5US79, A0A8J8XS73, G7P737
      Related
      ENSMFAP00000015295.1
      Conserved Domains (3) summary
      cd10313
      Location:191 → 540
      Deadenylase_CCR4a; C-terminal deadenylase domain of CCR4a, also known as CCR4-NOT transcription complex subunit 6
      COG4886
      Location:52 → 159
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:33 → 52
      LRR_1; leucine-rich repeat [structural motif]

    3. XM_005558809.4 → XP_005558866.1  CCR4-NOT transcription complex subunit 6 isoform X2

      See identical proteins and their annotated locations for XP_005558866.1

      Conserved Domains (3) summary
      cd10313
      Location:186 → 535
      Deadenylase_CCR4a; C-terminal deadenylase domain of CCR4a, also known as CCR4-NOT transcription complex subunit 6
      COG4886
      Location:52 → 158
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:33 → 52
      LRR_1; leucine-rich repeat [structural motif]

    4. XM_065547154.1 → XP_065403226.1  CCR4-NOT transcription complex subunit 6 isoform X1

      UniProtKB/TrEMBL
      A0A2K5US79, A0A8J8XS73, G7P737

    5. XM_045394672.2 → XP_045250607.1  CCR4-NOT transcription complex subunit 6 isoform X3

      Conserved Domains (3) summary
      cd10313
      Location:96 → 445
      Deadenylase_CCR4a; C-terminal deadenylase domain of CCR4a, also known as CCR4-NOT transcription complex subunit 6
      sd00033
      Location:4 → 26
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:3 → 44
      LRR_4; Leucine Rich repeats (2 copies)
    Nucleotide Protein
    Heading Accession and Version

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