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    CHUK component of inhibitor of nuclear factor kappa B kinase complex [ Falco cherrug (Saker falcon) ]

    Gene ID: 102053491, updated on 3-Aug-2024

    Summary

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    Gene symbol
    CHUK
    Gene description
    component of inhibitor of nuclear factor kappa B kinase complex
    See related
    EnsemblRapid:ENSFCHG00000003700
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Falco cherrug
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Falconiformes; Falconidae; Falco
    Orthologs
    human mouse all
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    Genomic context

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    See CHUK in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2023_04 current bFalChe1.pri (GCF_023634085.1) 9 NC_073705.1 (34240093..34271666)
    102 previous assembly F_cherrug_v1.0 (GCF_000337975.1) Unplaced Scaffold NW_004994938.1 (1019850..1059911)

    Chromosome 9 - NC_073705.1Genomic Context describing neighboring genes Neighboring gene arachidonate 5-lipoxygenase Neighboring gene CWF19 like cell cycle control factor 1 Neighboring gene small nucleolar RNA SNORA12 Neighboring gene ER lipid raft associated 1 Neighboring gene ADAM metallopeptidase domain 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables IkappaB kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tumor necrosis factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of IkappaB kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inhibitor of nuclear factor kappa-B kinase subunit alpha
    Names
    conserved helix-loop-helix ubiquitous kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_023634085.1-RS_2023_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bFalChe1.pri Primary Assembly

    Genomic

    1. NC_073705.1 Reference bFalChe1.pri Primary Assembly

      Range
      34240093..34271666
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_055720688.1 → XP_055576663.1  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1

    2. XM_055720689.1 → XP_055576664.1  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X2

    3. XM_027815340.2 → XP_027671141.1  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X2

      Conserved Domains (4) summary
      cd17046
      Location:308 → 384
      Ubl_IKKA_like; ubiquitin-like (Ubl) domain found in inhibitor of nuclear factor kappa-B kinases, IKK-alpha and IKK-beta, and similar proteins
      pfam12179
      Location:707 → 741
      IKKbetaNEMObind; I-kappa-kinase-beta NEMO binding domain
      pfam18397
      Location:383 → 656
      IKBKB_SDD; IQBAL scaffold dimerization domain
      cl21453
      Location:65 → 306
      PKc_like; Protein Kinases, catalytic domain

    4. XM_005446275.4 → XP_005446332.1  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X3

      Related
      ENSFCHP00000005941.1
      Conserved Domains (4) summary
      cd17046
      Location:261 → 337
      Ubl_IKKA_like; ubiquitin-like (Ubl) domain found in inhibitor of nuclear factor kappa-B kinases, IKK-alpha and IKK-beta, and similar proteins
      pfam12179
      Location:660 → 694
      IKKbetaNEMObind; I-kappa-kinase-beta NEMO binding domain
      pfam18397
      Location:336 → 609
      IKBKB_SDD; IQBAL scaffold dimerization domain
      cl21453
      Location:17 → 259
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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