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    LOC101286051 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [ Orcinus orca (killer whale) ]

    Gene ID: 101286051, updated on 2-Nov-2023

    Summary

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    Gene symbol
    LOC101286051
    Gene description
    1-acyl-sn-glycerol-3-phosphate acyltransferase delta
    See related
    EnsemblRapid:ENSOORG00010012591 EnsemblRapid:ENSOORG00010012655
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Orcinus orca
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
    Also known as
    PRKN; PARK2; AGPAT4
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    Genomic context

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    See LOC101286051 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 12 NC_064570.1 (5674106..7088721)

    Chromosome 12 - NC_064570.1Genomic Context describing neighboring genes Neighboring gene QKI, KH domain containing RNA binding Neighboring gene parkin coregulated Neighboring gene uncharacterized LOC125960624 Neighboring gene protein SET-like Neighboring gene uncharacterized LOC125960625 Neighboring gene long-chain-fatty-acid--CoA ligase 1-like Neighboring gene uncharacterized LOC117196274 Neighboring gene mitogen-activated protein kinase kinase kinase 4 Neighboring gene cytochrome c oxidase subunit NDUFA4-like Neighboring gene solute carrier family 22 member 3 Neighboring gene plasminogen

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064570.1 Chromosome 12 Reference mOrcOrc1.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin conjugating enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagy of mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cellular response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mitochondrion organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-acyl-sn-glycerol-3-phosphate acyltransferase delta; E3 ubiquitin-protein ligase parkin
    Names
    1-acylglycerol-3-phosphate O-acyltransferase 4
    parkin RBR E3 ubiquitin protein ligase
    parkinson protein 2, E3 ubiquitin protein ligase (parkin)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mOrcOrc1.1 Primary Assembly

    Genomic

    1. NC_064570.1 Reference mOrcOrc1.1 Primary Assembly

      Range
      5674106..7088721
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012536387.3 → XP_012391841.2  E3 ubiquitin-protein ligase parkin isoform X11

      Related
      ENSOORP00010016156.1, ENSOORT00010018653.1
      Conserved Domains (5) summary
      smart00647
      Location:313 → 375
      IBR; In Between Ring fingers
      cd01798
      Location:3 → 76
      Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
      pfam01485
      Location:413 → 453
      IBR; IBR domain, a half RING-finger domain
      pfam17978
      Location:228 → 318
      zf-RING_14; RING/Ubox like zinc-binding domain
      cd21382
      Location:146 → 229
      RING0_parkin; RING finger-like zinc-binding domain 0 of parkin

    2. XM_049695223.1 → XP_049551180.1  E3 ubiquitin-protein ligase parkin isoform X7

    3. XM_033403923.2 → XP_033259814.1  E3 ubiquitin-protein ligase parkin isoform X6

      Conserved Domains (5) summary
      cd07990
      Location:519 → 677
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      smart00647
      Location:313 → 375
      IBR; In Between Ring fingers
      cd01798
      Location:3 → 76
      Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
      pfam17978
      Location:228 → 318
      zf-RING_14; RING/Ubox like zinc-binding domain
      cd21382
      Location:146 → 229
      RING0_parkin; RING finger-like zinc-binding domain 0 of parkin

    4. XM_033403922.2 → XP_033259813.1  E3 ubiquitin-protein ligase parkin isoform X6

      Conserved Domains (5) summary
      cd07990
      Location:519 → 677
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      smart00647
      Location:313 → 375
      IBR; In Between Ring fingers
      cd01798
      Location:3 → 76
      Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
      pfam17978
      Location:228 → 318
      zf-RING_14; RING/Ubox like zinc-binding domain
      cd21382
      Location:146 → 229
      RING0_parkin; RING finger-like zinc-binding domain 0 of parkin

    5. XM_049695224.1 → XP_049551181.1  E3 ubiquitin-protein ligase parkin isoform X8

    6. XM_033403921.2 → XP_033259812.1  E3 ubiquitin-protein ligase parkin isoform X5

      Conserved Domains (5) summary
      cd07990
      Location:519 → 713
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      smart00647
      Location:313 → 375
      IBR; In Between Ring fingers
      cd01798
      Location:3 → 76
      Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
      pfam17978
      Location:228 → 318
      zf-RING_14; RING/Ubox like zinc-binding domain
      cd21382
      Location:146 → 229
      RING0_parkin; RING finger-like zinc-binding domain 0 of parkin

    7. XM_033403919.2 → XP_033259810.1  E3 ubiquitin-protein ligase parkin isoform X3

      Conserved Domains (5) summary
      cd07990
      Location:519 → 677
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      smart00647
      Location:313 → 375
      IBR; In Between Ring fingers
      cd01798
      Location:3 → 76
      Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
      pfam17978
      Location:228 → 318
      zf-RING_14; RING/Ubox like zinc-binding domain
      cd21382
      Location:146 → 229
      RING0_parkin; RING finger-like zinc-binding domain 0 of parkin

    8. XM_033403916.2 → XP_033259807.1  E3 ubiquitin-protein ligase parkin isoform X1

      Conserved Domains (5) summary
      PLN02380
      Location:477 → 802
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase
      smart00647
      Location:313 → 375
      IBR; In Between Ring fingers
      cd01798
      Location:3 → 76
      Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
      pfam17978
      Location:228 → 318
      zf-RING_14; RING/Ubox like zinc-binding domain
      cd21382
      Location:146 → 229
      RING0_parkin; RING finger-like zinc-binding domain 0 of parkin

    9. XM_033403918.2 → XP_033259809.1  E3 ubiquitin-protein ligase parkin isoform X3

      Conserved Domains (5) summary
      cd07990
      Location:519 → 677
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      smart00647
      Location:313 → 375
      IBR; In Between Ring fingers
      cd01798
      Location:3 → 76
      Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
      pfam17978
      Location:228 → 318
      zf-RING_14; RING/Ubox like zinc-binding domain
      cd21382
      Location:146 → 229
      RING0_parkin; RING finger-like zinc-binding domain 0 of parkin

    10. XM_033403920.2 → XP_033259811.1  E3 ubiquitin-protein ligase parkin isoform X4

      Conserved Domains (5) summary
      cd07990
      Location:519 → 706
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      smart00647
      Location:313 → 375
      IBR; In Between Ring fingers
      cd01798
      Location:3 → 76
      Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
      pfam17978
      Location:228 → 318
      zf-RING_14; RING/Ubox like zinc-binding domain
      cd21382
      Location:146 → 229
      RING0_parkin; RING finger-like zinc-binding domain 0 of parkin

    11. XM_033403917.2 → XP_033259808.1  E3 ubiquitin-protein ligase parkin isoform X2

      Conserved Domains (5) summary
      PLN02380
      Location:476 → 801
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase
      smart00647
      Location:312 → 374
      IBR; In Between Ring fingers
      cd01798
      Location:3 → 76
      Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
      pfam17978
      Location:227 → 317
      zf-RING_14; RING/Ubox like zinc-binding domain
      cd21382
      Location:145 → 228
      RING0_parkin; RING finger-like zinc-binding domain 0 of parkin

    12. XM_049695225.1 → XP_049551182.1  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X9

    13. XM_049695227.1 → XP_049551184.1  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X10

    14. XM_033403924.2 → XP_033259815.1  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X12

      Related
      ENSOORP00010016220.1, ENSOORT00010018722.1
      Conserved Domains (1) summary
      PLN02380
      Location:20 → 345
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase

    15. XM_004278870.4 → XP_004278918.1  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X12

      See identical proteins and their annotated locations for XP_004278918.1

      Conserved Domains (1) summary
      PLN02380
      Location:20 → 345
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase

    16. XM_033403925.2 → XP_033259816.1  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X12

      Conserved Domains (1) summary
      PLN02380
      Location:20 → 345
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase

    17. XM_033403926.2 → XP_033259817.1  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X12

      Conserved Domains (1) summary
      PLN02380
      Location:20 → 345
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase

    RNA

    1. XR_004476317.2 RNA Sequence

    2. XR_004476316.2 RNA Sequence

    3. XR_004476314.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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