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    IRAK3 interleukin 1 receptor associated kinase 3 [ Papio anubis (olive baboon) ]

    Gene ID: 101007837, updated on 8-Mar-2024

    Summary

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    Gene symbol
    IRAK3
    Gene description
    interleukin 1 receptor associated kinase 3
    See related
    Ensembl:ENSPANG00000002789
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Papio anubis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Papio
    Orthologs
    human mouse all
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    Genomic context

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    See IRAK3 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    104 current Panubis1.0 (GCF_008728515.1) 9 NC_044984.1 (60575087..60634112)
    103 previous assembly Panu_3.0 (GCF_000264685.3) 11 NC_018162.2 (61976706..62036340)

    Chromosome 9 - NC_044984.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110740704 Neighboring gene LLP homolog, long-term synaptic facilitation factor Neighboring gene transmembrane BAX inhibitor motif containing 4 Neighboring gene DNA helicase B Neighboring gene small nucleolar RNA U13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in interleukin-1-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of interleukin-12 production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of tumor necrosis factor production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-1 receptor-associated kinase 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Papio anubis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Panubis1.0 Primary Assembly

    Genomic

    1. NC_044984.1 Reference Panubis1.0 Primary Assembly

      Range
      60575087..60634112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003906738.4 → XP_003906787.1  interleukin-1 receptor-associated kinase 3 isoform X1

      UniProtKB/TrEMBL
      A0A096NP69, A0A2I3NE31
      Related
      ENSPANP00000014793.1, ENSPANT00000010062.3
      Conserved Domains (3) summary
      cd08796
      Location:15 → 103
      Death_IRAK-M; Death domain of Interleukin 1 Receptor Associated Kinase-M
      cd14160
      Location:171 → 446
      PK_IRAK3; Pseudokinase domain of Interleukin-1 Receptor Associated Kinase 3
      pfam00069
      Location:165 → 441
      Pkinase; Protein kinase domain

    2. XM_009181151.4 → XP_009179415.1  interleukin-1 receptor-associated kinase 3 isoform X2

      UniProtKB/TrEMBL
      A0A2I3LS93, A0A2I3NE31
      Related
      ENSPANP00000026341.1, ENSPANT00000033783.2
      Conserved Domains (3) summary
      cd14160
      Location:110 → 385
      PK_IRAK3; Pseudokinase domain of Interleukin-1 Receptor Associated Kinase 3
      pfam00069
      Location:104 → 380
      Pkinase; Protein kinase domain
      cl14633
      Location:15 → 51
      DD; Death Domain Superfamily of protein-protein interaction domains
    Nucleotide Protein
    Heading Accession and Version

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