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    L3MBTL2 L3MBTL histone methyl-lysine binding protein 2 [ Pan paniscus (pygmy chimpanzee) ]

    Gene ID: 100983870, updated on 10-Oct-2024

    Summary

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    Gene symbol
    L3MBTL2
    Gene description
    L3MBTL histone methyl-lysine binding protein 2
    See related
    Ensembl:ENSPPAG00000040643
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan paniscus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See L3MBTL2 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 23 NC_085927.1 (51038016..51064031)
    RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 22 NC_073271.1 (53737939..53763951)

    Chromosome 23 - NC_085927.1Genomic Context describing neighboring genes Neighboring gene E1A binding protein p300 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC117977418 Neighboring gene chondroadherin like Neighboring gene Ran GTPase activating protein 1 Neighboring gene zinc finger CCCH-type containing 7B Neighboring gene uncharacterized LOC129395166 Neighboring gene TEF transcription factor, PAR bZIP family member

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables methylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lethal(3)malignant brain tumor-like protein 2
    Names
    L3MBTL2, polycomb repressive complex 1 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Genomic

    1. NC_085927.1 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

      Range
      51038016..51064031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003814621.5 → XP_003814669.2  lethal(3)malignant brain tumor-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A2R9C1E1
      Conserved Domains (2) summary
      smart00561
      Location:511 → 604
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam02820
      Location:433 → 504
      MBT; mbt repeat

    2. XM_034949291.3 → XP_034805182.1  lethal(3)malignant brain tumor-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A2R9C1E1
      Conserved Domains (2) summary
      smart00561
      Location:517 → 610
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam02820
      Location:439 → 510
      MBT; mbt repeat

    3. XM_063603326.1 → XP_063459396.1  lethal(3)malignant brain tumor-like protein 2 isoform X4

    4. XM_063603325.1 → XP_063459395.1  lethal(3)malignant brain tumor-like protein 2 isoform X4

    5. XM_063603324.1 → XP_063459394.1  lethal(3)malignant brain tumor-like protein 2 isoform X1

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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