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    RASGEF1B RasGEF domain family member 1B [ Gallus gallus (chicken) ]

    Gene ID: 100859744, updated on 3-Dec-2024

    Summary

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    Symbol
    RASGEF1Bprovided by CGNC
    Full Name
    RasGEF domain family member 1Bprovided by CGNC
    Primary source
    CGNC:63405
    See related
    Ensembl:ENSGALG00010002880
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See RASGEF1B in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (45052923..45182306)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (44993031..45122480)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110559 Neighboring gene bone morphogenetic protein 3 Neighboring gene uncharacterized LOC107051741 Neighboring gene protein kinase, cGMP-dependent, type II Neighboring gene polycystin 2, transient receptor potential cation channel Neighboring gene secreted phosphoprotein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ras-GEF domain-containing family member 1B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      45052923..45182306
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046941296.1 → XP_046797252.1  ras-GEF domain-containing family member 1B isoform X2

      UniProtKB/TrEMBL
      A0A8V0XEL8

    2. XM_046941299.1 → XP_046797255.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8

    3. XM_025149791.3 → XP_025005559.1  ras-GEF domain-containing family member 1B isoform X1

      UniProtKB/TrEMBL
      A0A8V0XBP2
      Related
      ENSGALP00010004091.1, ENSGALT00010006682.1
      Conserved Domains (2) summary
      cd06224
      Location:85 → 208
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:251 → 445
      RasGEF; RasGEF domain

    4. XM_025149792.3 → XP_025005560.1  ras-GEF domain-containing family member 1B isoform X2

      UniProtKB/TrEMBL
      A0A8V0XEL8
      Conserved Domains (2) summary
      cd06224
      Location:47 → 170
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:213 → 407
      RasGEF; RasGEF domain

    5. XM_046941298.1 → XP_046797254.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8
      Related
      ENSGALP00010004090.1, ENSGALT00010006681.1

    6. XM_046941302.1 → XP_046797258.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8
      Related
      ENSGALP00010004080.1, ENSGALT00010006666.1

    7. XM_046941300.1 → XP_046797256.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8

    8. XM_004941094.5 → XP_004941151.2  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8
      Related
      ENSGALP00010004089.1, ENSGALT00010006679.1
      Conserved Domains (2) summary
      cd06224
      Location:42 → 165
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:208 → 402
      RasGEF; RasGEF domain

    9. XM_046941297.1 → XP_046797253.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8

    10. XM_015276515.4 → XP_015132001.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8
      Related
      ENSGALP00010004084.1, ENSGALT00010006671.1
      Conserved Domains (2) summary
      cd06224
      Location:42 → 165
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:208 → 402
      RasGEF; RasGEF domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      44993031..45122480
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046917552.1 → XP_046773508.1  ras-GEF domain-containing family member 1B isoform X2

      UniProtKB/TrEMBL
      A0A8V0XEL8

    2. XM_046917554.1 → XP_046773510.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8

    3. XM_040669656.2 → XP_040525590.1  ras-GEF domain-containing family member 1B isoform X1

      UniProtKB/TrEMBL
      A0A8V0XBP2
      Conserved Domains (2) summary
      cd06224
      Location:85 → 208
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:251 → 445
      RasGEF; RasGEF domain

    4. XM_040669657.2 → XP_040525591.1  ras-GEF domain-containing family member 1B isoform X2

      UniProtKB/TrEMBL
      A0A8V0XEL8
      Conserved Domains (2) summary
      cd06224
      Location:47 → 170
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:213 → 407
      RasGEF; RasGEF domain

    5. XM_046917553.1 → XP_046773509.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8

    6. XM_046917556.1 → XP_046773512.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8

    7. XM_046917555.1 → XP_046773511.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8

    8. XM_040669658.2 → XP_040525592.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8
      Conserved Domains (2) summary
      cd06224
      Location:42 → 165
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:208 → 402
      RasGEF; RasGEF domain

    9. XM_040669660.2 → XP_040525594.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8
      Conserved Domains (2) summary
      cd06224
      Location:42 → 165
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:208 → 402
      RasGEF; RasGEF domain

    10. XM_040669659.2 → XP_040525593.1  ras-GEF domain-containing family member 1B isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U7F8, A0A8V0XEL8
      Conserved Domains (2) summary
      cd06224
      Location:42 → 165
      REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
      pfam00617
      Location:208 → 402
      RasGEF; RasGEF domain
    Nucleotide Protein
    Heading Accession and Version

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