U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    KMT2D lysine methyltransferase 2D [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100441715, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    KMT2D
    Gene description
    lysine methyltransferase 2D
    Locus tag
    CR201_G0039521
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Also known as
    MLL2
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See KMT2D in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    56
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 10 NC_071995.2 (46782700..46823990, complement)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 12 NC_071997.1 (46785263..46824821, complement)

    Chromosome 10 - NC_071995.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112135731 Neighboring gene dendrin Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 1 Neighboring gene uncharacterized LOC129049127 Neighboring gene RHEB like 1 Neighboring gene desert hedgehog signaling molecule

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K4 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MLL3/4 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    histone-lysine N-methyltransferase 2D
    Names
    myeloid/lymphoid or mixed-lineage leukemia 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071995.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      46782700..46823990 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054527204.2 → XP_054383179.1  histone-lysine N-methyltransferase 2D isoform X2

      UniProtKB/TrEMBL
      A0A2J8SYR9

    2. XM_024256441.3 → XP_024112209.2  histone-lysine N-methyltransferase 2D isoform X6

      UniProtKB/TrEMBL
      A0A2J8SYR9

    3. XM_054527205.2 → XP_054383180.1  histone-lysine N-methyltransferase 2D isoform X3

      UniProtKB/TrEMBL
      A0A2J8SYR9

    4. XM_054527206.2 → XP_054383181.1  histone-lysine N-methyltransferase 2D isoform X4

      UniProtKB/TrEMBL
      A0A2J8SYR9

    5. XM_054527207.2 → XP_054383182.1  histone-lysine N-methyltransferase 2D isoform X5

      UniProtKB/TrEMBL
      A0A2J8SYR9

    6. XM_054527203.2 → XP_054383178.1  histone-lysine N-methyltransferase 2D isoform X1

      UniProtKB/TrEMBL
      A0A2J8SYR9
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.