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    rigi RNA sensor RIG-I [ Salmo salar (Atlantic salmon) ]

    Gene ID: 100302577, updated on 12-Sep-2024

    Summary

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    Gene symbol
    rigi
    Gene description
    RNA sensor RIG-I
    See related
    Ensembl:ENSSSAG00000119673
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Salmo salar
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salmo
    Also known as
    ddx58; rig-i
    Orthologs
    human zebrafish all
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    Genomic context

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    See rigi in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    102 current Ssal_v3.1 (GCF_905237065.1) Unplaced Scaffold NW_025550412.1 (172913..213552)
    100 previous assembly ICSASG_v2 (GCF_000233375.1) ssa18 NC_027317.1 (70356478..70372550)
    100 previous assembly ICSASG_v2 (GCF_000233375.1) Unplaced Scaffold NW_012344123.1 (3168..17491)

    NW_025550412.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106578232 Neighboring gene uncharacterized LOC123739377 Neighboring gene mucin-19 Neighboring gene dickkopf-related protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial antiviral signaling protein plays a major role in induction of the fish innate immune response against RNA and DNA viruses. Biacchesi S, et al. J Virol, 2009 Aug. PMID 19474100, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    antiviral innate immune response receptor RIG-I; probable ATP-dependent RNA helicase DDX58
    Names
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
    DExD/H-box helicase 58
    retinoic acid-inducible gene-I
    NP_001157171.1
    XP_045569699.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163699.1 → NP_001157171.1  antiviral innate immune response receptor RIG-I

      See identical proteins and their annotated locations for NP_001157171.1

      Status: PROVISIONAL

      Source sequence(s)
      FN178459
      UniProtKB/TrEMBL
      C7C1L7
      Conserved Domains (7) summary
      COG1111
      Location:269 → 800
      MPH1; ERCC4-related helicase [Replication, recombination and repair]
      cd00046
      Location:283 → 437
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd08816
      Location:2 → 91
      CARD_RIG-I_r1; Caspase activation and recruitment domain found in RIG-I, first repeat
      cd08817
      Location:99 → 190
      CARD_RIG-I_r2; Caspase activation and recruitment domain found in RIG-I, second repeat
      cd15805
      Location:835 → 946
      RIG-I_C; C-terminal domain of Retinoic acid-inducible gene (RIG)-I protein, a cytoplasmic viral RNA receptor
      cd12090
      Location:496 → 627
      MDA5_ID; Insert domain of MDA5
      pfam00271
      Location:636 → 763
      Helicase_C; Helicase conserved C-terminal domain

    RefSeqs of Annotated Genomes: Salmo salar Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Ssal_v3.1

    Genomic

    1. NW_025550412.1 Reference Ssal_v3.1

      Range
      172913..213552
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_045713743.1 → XP_045569699.1  probable ATP-dependent RNA helicase DDX58 isoform X1

      Related
      ENSSSAP00000179918.1, ENSSSAT00000192441.1
    Nucleotide Protein
    Heading Accession and Version

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