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    micall1a MICAL-like 1a [ Danio rerio (zebrafish) ]

    Gene ID: 100149741, updated on 4-Jan-2025

    Summary

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    Official Symbol
    micall1aprovided by ZNC
    Official Full Name
    MICAL-like 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-110119-1
    See related
    Ensembl:ENSDARG00000079811 AllianceGenome:ZFIN:ZDB-GENE-110119-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    micall1; wu:fb81a07
    Summary
    Predicted to enable metal ion binding activity. Is expressed in several structures, including integument; pectoral fin; pronephric duct; thyroid follicle; and yolk syncytial layer. Orthologous to human MICALL1 (MICAL like 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See micall1a in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (21536445..21571396)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (19476235..19510909)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene calcium channel, voltage-dependent, gamma subunit 4a Neighboring gene proteasome 26S subunit, non-ATPase 12 Neighboring gene si:dkey-43k4.3 Neighboring gene protein phosphatase 1, regulatory subunit 12C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification and expression analysis of mical family genes in zebrafish. Xue Y, et al. J Genet Genomics, 2010 Oct. PMID 21035094
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MICAL-like protein 1
    Names
    MICAL-like 1
    molecule interacting with CasL-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      21536445..21571396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001922140.7 → XP_001922175.2  MICAL-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M1QV63, E7FA45
      Related
      ENSDARP00000098869.3, ENSDART00000113911.4
      Conserved Domains (3) summary
      cd09444
      Location:161 → 215
      LIM_Mical_like_1; This domain belongs to the LIM domain family which are found on Mical (molecule interacting with CasL) like proteins
      pfam00307
      Location:5 → 102
      CH; Calponin homology (CH) domain
      pfam12130
      Location:683 → 819
      DUF3585; Protein of unknown function (DUF3585)

    2. XM_009302319.4 → XP_009300594.1  MICAL-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M3B0D6
      Conserved Domains (3) summary
      cd09444
      Location:161 → 215
      LIM_Mical_like_1; This domain belongs to the LIM domain family which are found on Mical (molecule interacting with CasL) like proteins
      pfam00307
      Location:5 → 102
      CH; Calponin homology (CH) domain
      pfam12130
      Location:669 → 805
      DUF3585; Protein of unknown function (DUF3585)
    Nucleotide Protein Strain
    Heading Accession and Version

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