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    Prr35 proline rich 35 [ Mus musculus (house mouse) ]

    Gene ID: 100034748, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Prr35provided by MGI
    Official Full Name
    proline rich 35provided by MGI
    Primary source
    MGI:MGI:2442713
    See related
    Ensembl:ENSMUSG00000025727 AllianceGenome:MGI:2442713
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A93001711Rik; A930017K11Rik
    Summary
    Is expressed in brain; male reproductive gland or organ; and metanephros. Orthologous to human PRR35 (proline rich 35). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 3.8), kidney adult (RPKM 3.2) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Prr35 in Genome Data Viewer
    Location:
    17 A3.3; 17 13.03 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (26165353..26171539, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25946379..25952573, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene Rab40C, member RAS oncogene family Neighboring gene cytochrome c oxidase subunit 7C, pseudogene 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:26056925-26057108 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class Q Neighboring gene RIKEN cDNA gene D630044L22 gene Neighboring gene NHL repeat containing 4 Neighboring gene calpain 15 Neighboring gene RIKEN cDNA 1700022N22 gene Neighboring gene RAB11 family interacting protein 3 (class II)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    proline-rich protein 35

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358019.1 → NP_001344948.1  proline-rich protein 35

      Status: VALIDATED

      Source sequence(s)
      AK044505, AW124301
      Consensus CDS
      CCDS89026.1
      UniProtKB/TrEMBL
      E0CXQ2
      Related
      ENSMUSP00000125106.2, ENSMUST00000162431.2
      Conserved Domains (2) summary
      PHA03247
      Location:94 → 539
      PHA03247; large tegument protein UL36; Provisional
      pfam15269
      Location:17 → 70
      zf-C2H2_7; Zinc-finger

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      26165353..26171539 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249393.2 → XP_030105253.1  proline-rich protein 35 isoform X1

      UniProtKB/TrEMBL
      E0CXQ2
      Conserved Domains (2) summary
      PHA03247
      Location:94 → 539
      PHA03247; large tegument protein UL36; Provisional
      pfam15269
      Location:17 → 70
      zf-C2H2_7; Zinc-finger

    2. XM_030249394.2 → XP_030105254.1  proline-rich protein 35 isoform X1

      UniProtKB/TrEMBL
      E0CXQ2
      Conserved Domains (2) summary
      PHA03247
      Location:94 → 539
      PHA03247; large tegument protein UL36; Provisional
      pfam15269
      Location:17 → 70
      zf-C2H2_7; Zinc-finger
    Nucleotide Protein Strain
    Heading Accession and Version

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