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    pimr214 Pim proto-oncogene, serine/threonine kinase, related 214 [ Danio rerio (zebrafish) ]

    Gene ID: 100002647, updated on 4-Jan-2025

    Summary

    Official Symbol
    pimr214provided by ZNC
    Official Full Name
    Pim proto-oncogene, serine/threonine kinase, related 214provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-141219-38
    See related
    Ensembl:ENSDARG00000104625 AllianceGenome:ZFIN:ZDB-GENE-141219-38
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch73-80e1.4
    Summary
    Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to act upstream of or within negative regulation of apoptotic process and protein phosphorylation. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See pimr214 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (12358780..12361784)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (12350740..12362937)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 172 Neighboring gene serine/threonine-protein kinase pim-2-like Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 169 Neighboring gene RERG/RAS-like a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Pim proto-oncogene, serine/threonine kinase, related 214; serine/threonine-protein kinase pim-2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      12358780..12361784
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021475245.2XP_021330920.1  serine/threonine-protein kinase pim-2-like isoform X1

      UniProtKB/TrEMBL
      A0A8M3ARC8, A0A8M9QBU5
      Related
      ENSDARP00000141378.1, ENSDART00000172557.2
      Conserved Domains (1) summary
      cl21453
      Location:2255
      PKc_like; Protein Kinases, catalytic domain
    2. XM_068220579.1XP_068076680.1  serine/threonine-protein kinase pim-2-like isoform X2

      UniProtKB/TrEMBL
      A0A8M3ARC8