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    ube2g1b ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast) [ Danio rerio (zebrafish) ]

    Gene ID: 100000479, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ube2g1bprovided by ZNC
    Official Full Name
    ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2939
    See related
    Ensembl:ENSDARG00000069527 AllianceGenome:ZFIN:ZDB-GENE-040426-2939
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ube2g1; zgc:55321; wu:fc68b05; wu:fc75g08; wu:fk32c04
    Summary
    Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Orthologous to human UBE2G1 (ubiquitin conjugating enzyme E2 G1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ube2g1b in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (17031635..17037902, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (16994999..17001266, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene GPN-loop GTPase 3 Neighboring gene actin related protein 2/3 complex, subunit 3 Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2b Neighboring gene BCR activator of RhoGEF and GTPase Neighboring gene uncharacterized LOC137488793

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The African coelacanth genome provides insights into tetrapod evolution. Amemiya CT, et al. Nature, 2013 Apr 18. PMID 23598338, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC55321, MGC86866

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-conjugating enzyme E2G 1b
    Names
    ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)
    ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)
    NP_998695.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213530.1 → NP_998695.1  ubiquitin-conjugating enzyme E2G 1b

      See identical proteins and their annotated locations for NP_998695.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045309
      UniProtKB/TrEMBL
      Q7ZW32
      Related
      ENSDARP00000092037.3, ENSDART00000101263.4
      Conserved Domains (2) summary
      COG5078
      Location:1 → 163
      COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      pfam00179
      Location:9 → 160
      UQ_con; Ubiquitin-conjugating enzyme

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      17031635..17037902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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