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    rab32b RAB32b, member RAS oncogene family [ Danio rerio (zebrafish) ]

    Gene ID: 100000199, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rab32bprovided by ZNC
    Official Full Name
    RAB32b, member RAS oncogene familyprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090821-4
    See related
    Ensembl:ENSDARG00000041165 AllianceGenome:ZFIN:ZDB-GENE-090821-4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport and melanosome organization. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be located in Golgi apparatus; membrane; and vesicle. Predicted to be active in melanosome; mitochondrion; and trans-Golgi network. Orthologous to human RAB32 (RAB32, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See rab32b in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (7363927..7379582, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (7207914..7214377, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene SAM and SH3 domain containing 1b Neighboring gene syntaxin binding protein 5b (tomosyn) Neighboring gene si:ch211-278p9.1 Neighboring gene glutamate receptor, metabotropic 1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut. Park J, et al. Dev Cell, 2019 Oct 7. PMID 31474562, Free PMC Article
    2. Rab32 and Rab38 genes in chordate pigmentation: an evolutionary perspective. Coppola U, et al. BMC Evol Biol, 2016 Jan 27. PMID 26818140, Free PMC Article
    3. A plasmid library of full-length zebrafish rab proteins for in vivo cell biology. Hall TE, et al. Cell Logist, 2017. PMID 28396820, Free PMC Article
    4. Pigmentation pathway evolution after whole-genome duplication in fish. Braasch I, et al. Genome Biol Evol, 2009 Nov 25. PMID 20333216, Free PMC Article
    5. Temporal pattern of loss/persistence of duplicate genes involved in signal transduction and metabolic pathways after teleost-specific genome duplication. Sato Y, et al. BMC Evol Biol, 2009 Jun 5. PMID 19500364, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in trans-Golgi network IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ras-related protein Rab-32

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      7363927..7379582 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017351720.3 → XP_017207209.2  ras-related protein Rab-32 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q6D4
      Related
      ENSDARP00000060335.7, ENSDART00000060336.8
      Conserved Domains (1) summary
      cd04107
      Location:17 → 211
      Rab32_Rab38; Rab GTPase families 18 (Rab18) and 32 (Rab32)

    2. XM_021467286.2 → XP_021322961.1  ras-related protein Rab-32 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PV84
      Conserved Domains (1) summary
      cl21455
      Location:17 → 167
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394976.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      33503..49158 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473080.2 → XP_021328755.1  ras-related protein Rab-32 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q6D4
      Conserved Domains (1) summary
      cd04107
      Location:17 → 211
      Rab32_Rab38; Rab GTPase families 18 (Rab18) and 32 (Rab32)

    2. XM_021473079.2 → XP_021328754.1  ras-related protein Rab-32 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PV84
      Conserved Domains (1) summary
      cl21455
      Location:17 → 167
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version

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