Radiation therapy toxicity association with abnormal transcriptional response to DNA damage
Summary:
Analysis of UV and IR irradiated lymphoblastoid cell lines derived from the peripheral blood of patients with acute radiation toxicity. Samples taken 2 months after the completion of radiation therapy. Results provide insight into the role of the response to DNA damage in radiation toxicity.
GPL8300:
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Citation:
Rieger KE, Hong WJ, Tusher VG, Tang J et al. Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Proc Natl Acad Sci U S A 2004 Apr 27;101(17):6635-40. PMID: 15096622