Pulmonary CDC11c+ cells from young and middle-age animals
Summary:
Analysis of pulmonary CDC11c+ cells from 6-8 week and 10-13 month old C57BL/6 animals. CDC11c+ cells are key modulators of the immune response in the lung. Results provide insight into molecular mechanisms underlying the decline in immune function associated with aging.
Vijay R, Hua X, Meyerholz DK, Miki Y et al. Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection. J Exp Med 2015 Oct 19;212(11):1851-68. PMID: 26392224