Peptidyl-prolyl cis/trans isomerase Pin1 deficiency effect on prostate cancer cells
Summary:
Analysis of prostate cancer (PC) cell lines LNCap (androgen-dependent) and DU145 (androgen-independent) following siRNA-mediated knockdown of Peptidyl-prolyl cis/trans isomerase Pin1. Results provide insight into molecular mechanisms underlying Pin1 modulation of both PC two cell lines.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Kanaoka R, Kushiyama A, Seno Y, Nakatsu Y et al. Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines. PLoS One 2015;10(6):e0127467. PMID: 26039047