Analysis of livers of animals following bile duct ligation to induce extrahepatic cholestasis. Biliary tract obstruction is a common mechanism of hepatic injury. Results provide insight into molecular mechanisms that influence injury and repair in cholestatic liver disease.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Wang H, Vohra BP, Zhang Y, Heuckeroth RO. Transcriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice. Hepatology 2005 Nov;42(5):1099-108. PMID: 16250054
