Androgen effect on carboxyl terminal-binding protein 2-deficient prostate cancer cell line
Summary:
Analysis of androgen receptor (AR)-positive LNCaP prostate cancer cells depleted for carboxyl terminal-binding protein 2 (CTBP2) then treated with the androgen, dihydrotestosterone (DHT). Results provide insight into the molecular effects of CtBP2 knockdown on AR-mediated gene regulation.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Takayama K, Suzuki T, Fujimura T, Urano T et al. CtBP2 modulates the androgen receptor to promote prostate cancer progression. Cancer Res 2014 Nov 15;74(22):6542-53. PMID: 25228652