Glucose effect on steroid receptor coactivator 1 deficient-A549 lung cancer epithelial cell line
Summary:
Analysis of highly glycolytic A549 lung cancer cells depleted for steroid receptor coactivator SRC-1 and grown in the absence of glucose. SRC-1 promotes gluconeogenesis and glycemia. Results provide insight into the role of SRC-1 in glycolytic cancer cells undergoing glucose deprivation.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Motamed M, Rajapakshe KI, Hartig SM, Coarfa C et al. Steroid receptor coactivator 1 is an integrator of glucose and NAD+/NADH homeostasis. Mol Endocrinol 2014 Mar;28(3):395-405. PMID: 24438340
