Ethanol effect on myoblast differentiation in vitro
Summary:
Analysis of C2C12 cells cultured for up to 3 days in differentiation medium containing ethanol. Chronic alcoholics suffer from weakness and locomotor difficulty resulting from muscle damage. Results provide insight into the signaling pathways affected by ethanol in differentiating myoblasts.
Arya MA, Tai AK, Wooten EC, Parkin CD et al. Notch pathway activation contributes to inhibition of C2C12 myoblast differentiation by ethanol. PLoS One 2013;8(8):e71632. PMID: 23977095
