Nitric oxide synthase-2 depletion effect on glioma stem cell
Summary:
Analysis of glioma stem cells depleted for nitric oxide synthase-2 (NOS2). Glioma stem cells isolated from two different human glioma xenografts. NOS2 catalyzes the formation of nitric oxide. Results provide insight into the role of NOS2 in glioma stem cell profileration and tumor growth.
Eyler CE, Wu Q, Yan K, MacSwords JM et al. Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell 2011 Jul 8;146(1):53-66. PMID: 21729780