Pristane-induced arthritis effect on AIRmax and AIRmin acute inflammation model: footpad
Summary:
Analysis of footpad from animals with high (AIRmax) or low (AIRmin) acute inflammation following 2 injections of pristine at 60-day intervals. Arthritis development was examined twice weekly for 160 days. Results provide insight into molecular mechanisms distinguishing the AIRmax and AIRmin models.
De Franco M, Peters LC, Correa MA, Galvan A et al. Pristane-induced arthritis loci interact with the Slc11a1 gene to determine susceptibility in mice selected for high inflammation. PLoS One 2014;9(2):e88302. PMID: 24505471