Pristane-induced arthritis effect on AIRmax high acute inflammation model: footpad
Summary:
Analysis of footpad from outbred animals with high (AIRmax) acute inflammation following two injections of pristine at 60-day intervals. Arthritis development was examined twice weekly for 160 days. Results provide insight into molecular mechanisms underlying arthritis induction and progression.
De Franco M, Peters LC, Correa MA, Galvan A et al. Pristane-induced arthritis loci interact with the Slc11a1 gene to determine susceptibility in mice selected for high inflammation. PLoS One 2014;9(2):e88302. PMID: 24505471