Mechanistic Indicators of Asthma (MICA) cohort: peripheral blood
Summary:
Analysis of peripheral blood from asthmatic and non-asthmatic children (ages 9 to 13), participants of the MICA study conducted by the EPA from 11/2006 to 01/2007 in Detroit, MI. These results, together with clinical biomarker measurements, may help to differentiate asthmatics from non-asthmatics.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
Williams-DeVane CR, Reif DM, Hubal EC, Bushel PR et al. Decision tree-based method for integrating gene expression, demographic, and clinical data to determine disease endotypes. BMC Syst Biol 2013 Nov 4;7:119. PMID: 24188919
George BJ, Reif DM, Gallagher JE, Williams-DeVane CR et al. Data-driven asthma endotypes defined from blood biomarker and gene expression data. PLoS One 2015;10(2):e0117445. PMID: 25643280
