Sparsely or densely ionizing radiation effect on mammary gland: dose response and time course
Summary:
Analysis of mammary gland from females irradiated at 10 wks of age with varying doses of sparsely or densely ionizing radiation (IR). Mammary tissue collected up to 12 wks post-IR. Results provide insight into molecular response of mammary tissue exposed to different radiation qualities and doses.
Tang J, Fernandez-Garcia I, Vijayakumar S, Martinez-Ruis H et al. Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors. Stem Cells 2014 Mar;32(3):649-61. PMID: 24038768
