Analysis of FACS-sorted CD45-Ter119-Sca-1-CD29+Cxcr4+ skeletal muscle precursor (SMP) cells from young, middle-aged, and old C57BL/6 males. Results provide insight into the molecular mechanisms underlying age-related skeletal muscle and stem cell dysfunction.
Sinha M, Jang YC, Oh J, Khong D et al. Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle. Science 2014 May 9;344(6184):649-52. PMID: 24797481
