Proliferator-activated receptor gamma agonist rosiglitazone effect on extravillous cytotrophoblasts in vitro
Summary:
Analysis of EVCTs isolated from first trimester placenta and treated with rosiglitazone, a PPARγ agonist. EVCT invasion into the uterus is critical for placental and fetal development. Results provide insight into the molecular basis of PPARγ-mediated regulation of EVCT invasion in vitro.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citations:
Segond N, Degrelle SA, Berndt S, Clouqueur E et al. Transcriptome analysis of PPARγ target genes reveals the involvement of lysyl oxidase in human placental cytotrophoblast invasion. PLoS One 2013;8(11):e79413. PMID: 24265769
Liu F, Rouault C, Guesnon M, Zhu W et al. Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts. PPAR Res 2020;2020:9210748. PMID: 32308672
