DataSet Record GDS4845: Expression Profiles Data Analysis Tools Sample Subsets
Title: Streptozotocin induced type 1 diabetes: liver
Cluster AnalysisGDS4845 Cluster Image
Download
Summary: Analysis of liver from C57BL/6N males treated with streptozotocin (STZ) to induce type 1 diabetes (T1D). Liver mitochondria of STZ males showed increased oxygen consumption. Results provide insight into molecular mechanisms underlying the enhanced performance of T1D STZ liver mitochondria.
Organism: Mus musculus
Platform: GPL6246: [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Citations:
  • Franko A, von Kleist-Retzow JC, Neschen S, Wu M et al. Liver adapts mitochondrial function to insulin resistant and diabetic states in mice. J Hepatol 2014 Apr;60(4):816-23. PMID: 24291365
  • Franko A, Huypens P, Neschen S, Irmler M et al. Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice. Diabetes 2016 Sep;65(9):2540-52. PMID: 27284107
Reference Series: GSE39752 Sample count: 13
Value type: transformed count Series published: 2013/12/10