Analysis of effect of DACH1 in breast cancer cell line MDA-MB-231. DACH1 induced by ponasterone A treatment for 0, 18 or 36 hours. DACH1 may regulate aberrant TGF beta signals that have role in breast cancer progression.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Wu K, Yang Y, Wang C, Davoli MA et al. DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. J Biol Chem 2003 Dec 19;278(51):51673-84. PMID: 14525983