Psoriasis non-lesional skin response to interferon-γ
Summary:
Analysis of non-lesional (NL) skin of psoriasis patients 24 hrs after a single intradermal injection of interferon-γ (IFN-γ) to the NL skin. Results suggest that IFN-γ may prime an inflammatory environment in the skin that shares many features with psoriasis.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Johnson-Huang LM, Suárez-Fariñas M, Pierson KC, Fuentes-Duculan J et al. A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin. J Invest Dermatol 2012 Apr;132(4):1177-87. PMID: 22277938
