Analysis of heme-cultured HRG-2 mutants. Heme-responsive gene-2 (HRG-2) is a hypodermal, heme-binding, type I membrane protein; cytochrome distribution is abnormal in HRG-2-deficient worms. Results provide insight into molecular mechanisms underlying the regulation of heme homeostasis by HRG-2.
GPL200:
[Celegans] Affymetrix C. elegans Genome Array
Citation:
Chen C, Samuel TK, Krause M, Dailey HA et al. Heme utilization in the Caenorhabditis elegans hypodermal cells is facilitated by heme-responsive gene-2. J Biol Chem 2012 Mar 16;287(12):9601-12. PMID: 22303006