Gamma-tocotrienol effect on breast cancer MCF-7 cells
Summary:
Analysis of MCF-7 cells treated with gamma-tocotrienol (γ-T3). Tocotrienols (T3s) inhibit the growth of various cancer cell lines without affecting normal cells. Results provide insight into the molecular mechanisms of action of T3s on cell death and other growth inhibitory pathways.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Patacsil D, Tran AT, Cho YS, Suy S et al. Gamma-tocotrienol induced apoptosis is associated with unfolded protein response in human breast cancer cells. J Nutr Biochem 2012 Jan;23(1):93-100. PMID: 21429729