Analysis of epididymal fat from 3 week-old ICR males undernourished in utero, but permitted catch-up growth (CUG) during suckling. CUG is a growth pattern associated with obesity and diabetes risk. Results provide insight into the molecular basis of the deleterious effects of CUG.
Isganaitis E, Jimenez-Chillaron J, Woo M, Chow A et al. Accelerated postnatal growth increases lipogenic gene expression and adipocyte size in low-birth weight mice. Diabetes 2009 May;58(5):1192-200. PMID: 19208909