Analysis of minor salivary glands with varying degrees of inflammation from Sjögren's syndrome (SS) patients. SS is a chronic autoimmune disease targeting salivary and lacrimal exocrine glands. Results provide insight into the molecular mechanisms underlying the immunopathology associated with SS.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Greenwell-Wild T, Moutsopoulos NM, Gliozzi M, Kapsogeorgou E et al. Chitinases in the salivary glands and circulation of patients with Sjögren's syndrome: macrophage harbingers of disease severity. Arthritis Rheum 2011 Oct;63(10):3103-15. PMID: 21618203