Ciliopathy-based photoreceptor degeneration model: time course
Summary:
Analysis of retina from PKD-2-247 (TGR) males at 1 and 3 months of age (i.e., before and after retinal vasoregression). The TGR model develops primary photoreceptor degeneration and secondary vasoregression. Results provide insight into molecular mechanisms underlying development of vasoregression.
GPL1355:
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Citation:
Feng Y, Wang Y, Li L, Wu L et al. Gene expression profiling of vasoregression in the retina--involvement of microglial cells. PLoS One 2011 Feb 17;6(2):e16865. PMID: 21379381