Retinoic acid effect on CD4+ T cells from spleen/lymph nodes
Summary:
Analysis of CD4+ T cells pooled from spleen and mesenteric/peripheral lymph nodes and cultured with exogenous retinoic acid (RA). Integrins are required for T cell migration to mucosal tissues. Results provide insight into the role of RA in the regulation of mucosal integrin expression in T cells.
Kang SG, Park J, Cho JY, Ulrich B et al. Complementary roles of retinoic acid and TGF-β1 in coordinated expression of mucosal integrins by T cells. Mucosal Immunol 2011 Jan;4(1):66-82. PMID: 20664575
