Analysis of C57BL/6 and CBA/CaH animals infected with Plasmodium berghei ANKA to induce experimental cerebral malaria (ECM). CM is a complication of P. falciparum infection. ECM in B6 and CBA displays many features of human CM. Results provide insight into the development of treatments for human CM.
Randall LM, Amante FH, McSweeney KA, Zhou Y et al. Common strategies to prevent and modulate experimental cerebral malaria in mouse strains with different susceptibilities. Infect Immun 2008 Jul;76(7):3312-20. PMID: 18474652