DataSet Record GDS3116: Expression Profiles Data Analysis Tools Sample Subsets
Title: Letrozole effect on breast cancer tumors
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Summary: Analysis of breast cancer tumors following treatment with letrozole for 14 days. The aromatase inhibitor letrozole is an anti-estrogen drug used to treat postmenopausal women with breast cancer. Results provide insight into the molecular mechanism of action of letrozole in breast cancer.
Organism: Homo sapiens
Platform: GPL96: [HG-U133A] Affymetrix Human Genome U133A Array
Citations:
  • Miller WR, Larionov AA, Renshaw L, Anderson TJ et al. Changes in breast cancer transcriptional profiles after treatment with the aromatase inhibitor, letrozole. Pharmacogenet Genomics 2007 Oct;17(10):813-26. PMID: 17885619
  • Miller WR, Larionov A. Changes in expression of oestrogen regulated and proliferation genes with neoadjuvant treatment highlight heterogeneity of clinical resistance to the aromatase inhibitor, letrozole. Breast Cancer Res 2010;12(4):R52. PMID: 20646288
Reference Series: GSE5462 Sample count: 116
Value type: count Series published: 2007/12/10