Examination of skeletal muscle from juvenile dermatomyositis (JDM) patients, a common pediatric inflammatory myopathy. Muscle biopsies processed singly or in mixed groups of two. Patients genotyped for TNFalpha which is associated with prolonged disease.
GPL80:
[Hu6800] Affymetrix Human Full Length HuGeneFL Array
Citation:
Tezak Z, Hoffman EP, Lutz JL, Fedczyna TO et al. Gene expression profiling in DQA1*0501+ children with untreated dermatomyositis: a novel model of pathogenesis. J Immunol 2002 Apr 15;168(8):4154-63. PMID: 11937576