DataSet Record GDS2411: Expression Profiles Data Analysis Tools Sample Subsets
Title: Transcription factor PU.1 knockdown effect on hematopoietic stem cells
Cluster AnalysisGDS2411 Cluster Image
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Summary: Analysis of preleukemic hematopoietic stem cells from animals knocked down for the transcription factor PU.1. PU.1 knockdown leads to acute myeloid leukemia in the animal. Results provide insight into the molecular changes preceding malignant transformation.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Steidl U, Rosenbauer F, Verhaak RG, Gu X et al. Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells. Nat Genet 2006 Nov;38(11):1269-77. PMID: 17041602
Reference Series: GSE5654 Sample count: 6
Value type: count Series published: 2006/10/15