Prostaglandin J2 effect on neuroblastoma cell line: time course
Summary:
Analysis of neuroblastoma SK-N-SH cells at various time points up to 24 hours following treatment with prostaglandin J2 (PGJ2), a neurotoxic product of inflammation. Results provide insight into mechanisms of PGJ2-induced accumulation/aggregation of ubiquitinated proteins and to neuronal cell death.
Wang Z, Aris VM, Ogburn KD, Soteropoulos P et al. Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells. J Biol Chem 2006 Jul 28;281(30):21377-21386. PMID: 16737963
