Retinitis pigmentosa 1 gene knockout effect on retinas: time course
Summary:
Analysis of retinas of animals disrupted for the retinitis pigmentosa 1 (RP1) gene. Animals examined up to postnatal day 21. Results provide insight into mechanisms underlying autosomal dominant progressive RP caused by RP1 mutations and identify molecules involved early in the disease process.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Liu J, Huang Q, Higdon J, Liu W et al. Distinct gene expression profiles and reduced JNK signaling in retinitis pigmentosa caused by RP1 mutations. Hum Mol Genet 2005 Oct 1;14(19):2945-58. PMID: 16126734
