Analysis of Kc-167 cells following knockdown of Enigma (Egm) using RNAi. Egm is a mitochondrial protein with homology to enzymes of the beta-oxidation of fatty acids. Results provide insight into the mechanisms underlying the increased oxidative stress tolerance conferred by decreased Egm levels.
Mourikis P, Hurlbut GD, Artavanis-Tsakonas S. Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila. Proc Natl Acad Sci U S A 2006 Jan 31;103(5):1307-12. PMID: 16434470