Ionizing radiation effect on lymphoid tissue of ATM protein kinase deficient mutants
Summary:
Analysis of lymph nodes from ATM-deficient males exposed to ionizing radiation (IR). ATM regulates the cellular network induced by DNA double-strand breaks and is often mutated in lymphoid tumors. Results identify parallel induction of ATM-dependent pro- and antiapoptotic signals in response to IR.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Rashi-Elkeles S, Elkon R, Weizman N, Linhart C et al. Parallel induction of ATM-dependent pro- and antiapoptotic signals in response to ionizing radiation in murine lymphoid tissue. Oncogene 2006 Mar 9;25(10):1584-92. PMID: 16314843