Type 1 diabetes model response to cyclophosphamide: time course
Summary:
Analysis of pancreatic islets from BDC2.5/NOD transgenics after treatment with 200 mg/kg cyclophosphamide (CY) at various time points up to 3 days. CY induces diabetes in BDC2.5/NOD transgenics. Results provide insight into molecular events accompanying the progression from insulitis to diabetes.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Matos M, Park R, Mathis D, Benoist C. Progression to islet destruction in a cyclophosphamide-induced transgenic model: a microarray overview. Diabetes 2004 Sep;53(9):2310-21. PMID: 15331540
